30DEC

Libyan International Conference for Health Sciences

The First Libyan International Conference for Health Sciences (2024): Open University, Tripoli, Libya
Mediterranean Journal of Pharmacy and Pharmaceutical Sciences
https://ppj.org.ly/article/doi/10.5281/zenodo.12601827

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences

Short communication

Determination of the structural parameters of Repaglinide in tablet: an antidiabetic drug, using Spectroscopic methods

Djawhara Haddad, Nasser Belboukhari, Khaled Sekkoum, Meriem Bouanini

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Abstract

The spectroscopy area provides molecular-level information about an anti-diabetic drug through qualitative and quantitative analysis, Repaglinide is an antidiabetic medication in the meglitinide class that is used to treat type II diabetes mellitus. The objective of this work was to characterize Repaglinide by using UV spectroscopy (UV), nuclear magnetic resonance (NMR), and infrared spectrometry (FTIR).  The UV results showed that the maximum absorption was at 208, 243, and 285 nm. The IR spectra obtained are consistent with those described in the literature. The NMR-1H spectra revealed information about the various hydrogen and carbon atoms in the molecule as well as their chemical surroundings. The provided methods were successfully employed to control a drug with great accuracy and precision.

Keywords

Repaglinide, FT-IR, NMR-1H, UV

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Submitted date:
06/02/2024

Reviewed date:
06/23/2024

Accepted date:
06/29/2024

Publication date:
06/30/2024

6681eaf3a9539562e250faa6 medjpps Articles
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Mediterr J Pharm Pharm Sci

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