30DEC

Libyan International Conference for Health Sciences

The First Libyan International Conference for Health Sciences (2024): Open University, Tripoli, Libya
Mediterranean Journal of Pharmacy and Pharmaceutical Sciences
https://ppj.org.ly/article/doi/10.5281/zenodo.6780474

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences

Review

Serum uric acid as an adjunct in the assessment of psychiatric disorders: an overview

Jagannadha R. Peela, Abdalla M. Jarari, Harshvaradhan Polamarasetty, Vaishnavi Kanisetti, Krishna Srivathsav Tadikonda, Anuradha Argi, Avinash K. Rawal

http://dx.doi.org/10.5281/zenodo.6780474 Mediterr J Pharm Pharm Sci, vol.2, n2, 6, 2022
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Abstract

Oxidative stress is due to altered levels of prooxidants and anti-oxidants in the body. This can lead to tissue damage especially, the central nervous system. Oxidative damage has been implicated in several disorders including some psychiatric disorders such as schizophrenia and major depressive disorder. Uric acid is an anti-oxidant that prevents tissue damage caused by oxidative stress. In this review, the reduced levels of serum uric acid in schizophrenia and depression are discussed. The effect of treatment in these disorders leading to increased serum uric acid levels is also reviewed.

Keywords

Major depressive disorder, oxidative stress, schizophrenia, uric acid

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Submitted date:
06/02/2022

Reviewed date:
06/22/2022

Accepted date:
06/28/2022

Publication date:
11/08/2024

672deab2a953957d0b2dd9c4 medjpps Articles
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