30DEC

Libyan International Conference for Health Sciences

The First Libyan International Conference for Health Sciences (2024): Open University, Tripoli, Libya
Mediterranean Journal of Pharmacy and Pharmaceutical Sciences
https://ppj.org.ly/article/doi/10.5281/zenodo.7479667

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences

review

Analysis of the association of vitamin D3, hemoglobin and ferritin with special respect to Libyan patients

Salsabil A. Ansari, Rana A. Boker, Mariam S. Alsaid, Roba F. Sherif, Fathi M. Sherif

Downloads: 0
Views: 158

Abstract

Anemia, iron deficiency and iron deficiency anemia are common blood disorders. The role of vitamin D was agreed to be regulating calcium and phosphate absorption and bone metabolism and its deficiency is observed as a crucial nutritional problem. Vitamin D is created under the skin by ultraviolet light. It is usually getting vitamins from the food; however, in the case of vitamin D, there simply are not enough rich food sources for people to get adequate amounts in their diet. Its effects on the prevention of diseases such as cardiovascular disease and anemia have received much attention recently. To get sufficient vitamin D, need to be exposed to sunshine or use supplements. Vitamin D3 was found in the largest population as a deficiency. With regard to hemoglobin the subject who has a less normal range of hemoglobin (19.05%) than the international normal range, and in ferritin the low population number was the subject whom has less normal range of ferritin than WHO normal range. The population that has low ferritin also has low vitamin D3 and variable hemoglobin. According to international guidelines, optimizing nutrition with daily or intermittent (1 to 3 times per week) iron supplementation, should be considered a first-line intervention in high-risk or high-prevalence groups. Although it is probably less effective than daily iron supplementation, intermittent iron appears to be a useful and cost-effective way of controlling anemia and iron deficiency anemia. This may indicate a positive relation between the low concentration parameter of vitamin D3 and ferritin level but no significant correlation with hemoglobin.

Keywords

Blood, ferritin, hemoglobin, Libya, vitamin D

References

  1. Rona Z (2010) Vitamin D: the sunshine vitamin. ISBN: 978-0-920470-82-4.
  2. Ross AC, Taylor CL, Yaktine AL, Del Valle HB (2011) Dietary reference intakes for calcium and vitamin D. ISBN: 978-0-309-16394-1.
  3. Holick MF (2007) Vitamin D deficiency 19. The New England Journal of Medicine. 357 (3): 266-281. doi: 10.1056/NEJMra070553
  4. DeLuca HF (2004) Overview of general physiologic features and functions of vitamin D. 80 (6S):1689S-1696S. doi: 10.1093/ajcn/80.6.1689S
  5. Bikle DD (2014) Vitamin D metabolism, mechanism of action, and clinical applications. Chemistry and Biology. 21 (3): 319-29. doi: 10.1016/j.chembiol.2013.12.016
  6. The International Society of Nephrology, Kidney International (1986) The metabolism and mechanism of action of 1,25-dihydroxyvitamin D3. 30: 793-803. doi: Nil.
  7. Holick MF (2017) The vitamin D deficiency pandemic: approaches for diagnosis, treatment and prevention. Reviews in Endocrine and Metabolic Disorders. 18: 153-165 doi: 10.1007/s11154-017-9424-1
  8.  Jones G (2012) Metabolism and biomarkers of vitamin D. Scandinavian Journal of Clinical and Laboratory Investigation. 72 (243S): 7-13. doi: 10.3109/00365513.2012.681892
  9. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, Murad MH, Weaver CM, Endocrine Society (2011) Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. The journal of Clinical Endocrinology and Metabolism. 96 (7): 1911-1130. doi: 10.1210/jc.2011-0385
  10. Holick MF, Chen TC (2008) Vitamin D deficiency: a worldwide problem with health consequences 1-4. American Journal of Clinical Nutrition. 87S: 1080S-106S. American Society for Nutrition. e1080-1086. doi: Nil.
  11. Adamson JW, Finch CA (1975) Hemoglobin function, oxygen affinity, and erythropoietin. Annual Review of Physiology. 37: 351-369. doi: Nil.
  12. Bunn HF (2016) Approach to the anemia's. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders. 621-623. ISBN: 9780323550871.
  13. Knovich MA, Storey JA, Coffman LG, Torti SV, Torti FM (2009) Ferritin for the clinician. Blood Reviews. 23 (3): 95-104. doi: 10.1016/j.blre.2008.08.001
  14. Yoon H, Bae NY, Gi MY, Park BY, Seong JM (2017) The association between serum ferritin and 25-hydroxyvitamin D and metabolic syndrome in Korean women: the Korea National Health and Nutrition Examination Survey 2010-2012. Journal of Clinical Biochemistry and Nutrition. 61 (1): 60-66. doi: 10.3164/jcbn.16-115
  15. Fuzi SFA, Mushtaq S (2019) Vitamin D3 supplementation for 8 weeks leads to improved haematological status following the consumption of an iron-fortified breakfast cereal: a double randomized controlled trail in iron-deficient women. British Journal of Nutrition. 121 (10): 1146-1157. doi: 10.1017/S0007114519000412

Submitted date:
08/15/2022

Reviewed date:
09/02/2022

Accepted date:
09/16/2022

Publication date:
07/07/2023

64a7ebb0a9539511e85ab565 medjpps Articles
Links & Downloads

Mediterr J Pharm Pharm Sci

Share this page
Page Sections